Leber congenital amaurosis and osteogenesis imperfecta are both genetic diseases demonstrating:
A dominant allele masks the expression of a recessive allele.
Recessive disorders tend to be more severe and produce symptoms earlier than dominant disorders.
Mendel crossed some yellow round pea plants with wrinkled green pea plants. The traits of yellow and round were dominant. In the first generation, the F1 generation all the offspring were;
According to widely accepted modern evolutionary ideas mitochondria originated in cells according to;
What percent of cases of Alzheimer disease are familial (inherited)?
The bodies of the Royal Romanovs, the ruling family of Russia in the early 1900s were exhumed in the 1990s and their DNA was sequenced. Geneticists found a variation in the mitochondrial DNA sequence among the royal family members. The variation was explained by the phenomena of:
Every phenotype, the trait that you observe, is caused by the combination of two alleles or the genotype, so for example, brown eye color is a phenotype which can be produced by a dominant allele (B) such that the genotype for brown eye color could be Bb or BB.
In order for a child to get the genetic based disease cystic fibrosis which of the following must occur?
Familial hypercholesterolemia is an autosomal dominant genetic disease wherein the disease carriers cannot take up cholesterol normally so that it builds up in the blood, so that homozygotes for the disease can die in childhood whereas heterozygotes don’t have heart attacks until they are young adults. This is an example of
The OCA2 gene confers eye color such that the recessive condition (two recessive alleles) results in:
The law of segregation states that alleles of a gene:
Genetic disease based on altered genes results in “loss of function” or “gain of function” which causes the disease and its symptoms. Huntington’s disease is caused by an abnormally long protein which causes symptoms. This would be classified as:
Using and understanding pedigrees are important today because they help families identify the risk of transmitting an inherited disease
A Punnet square follows transmission of alleles and is based on probability.
Protein tau can form sticky“tangles” as part of the cause of Alzheimer disease.
Amyloid plaques are the suspected cause of Alzheimer disease.
Since osteogenesis imperfecta can be the result of single gene defects in a number of different genes (genetic heterogeneity) parents who carry the defect in different genes from their partner can produce a child with this syndrome.
Achondroplastic dwarfism is considered a lethal genetic syndrome because;
LDL is the carrier of cholesterol in blood.
Austrian monk Gregor Mendel primarily worked with what kind of organisms to do his genetic work?
The control of most human traits by single genes is rare because most traits are the results of multiple genes like human eye color.
Because Huntington’s disease is so deadly most people alive who have it are children.
A phenotype is the trait that you see or can observe.
A single gene on chromosome 15 confers eye color by controlling melanin synthesis.